Luma Nutrition Berberine HCl 1,200mg – 60 Vegan Capsules | 97% Standardised Berberine

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Berberine HCl at 1,200mg per serving, standardised to 97% purity. 60 capsules.

What it is

Berberine is a yellow alkaloid found in several plants — barberry, goldenseal, Oregon grape, Chinese goldthread — and used in both Chinese and Ayurvedic traditions for centuries. It's had a great deal of research attention over the past decade, and it's one of the more pharmacologically active compounds sold as a supplement, which is the reason for the warnings below rather than a footnote to them.

The 97% standardisation is the specification worth checking: berberine content varies widely between products, and a stated purity lets you compare like with like. Vegan and gluten-free.

How to use

Take as directed on the pack, with food. Berberine is usually split across the day rather than taken in one dose, as it's poorly absorbed and can cause digestive upset in a single large amount.

Who it is for

For adults who can take berberine safely.

Please read the following carefully. Berberine interacts with more medications than almost anything else sold as a supplement.

Not for use during pregnancy, while trying to conceive, or while breastfeeding, and never give it to an infant. Berberine crosses the placenta and passes into breast milk, and in newborns it can displace bilirubin and cause a serious form of jaundice. This is the most important warning on this page.

Do not take it if you are on medication for diabetes — berberine lowers blood sugar, and combined with metformin, insulin or a sulfonylurea it can lower it further than intended.

Berberine inhibits CYP3A4, the liver enzyme that processes a large share of prescription drugs — the same enzyme grapefruit affects, which is why grapefruit carries warnings on so many medicines. That means it can raise blood levels of statins, ciclosporin, some blood thinners, and many others. If you take any prescribed medication, speak to a pharmacist before starting this. Not suitable for children.

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Food supplement. Not a substitute for a varied, balanced diet and healthy lifestyle. Do not exceed the recommended daily dose. Keep out of reach of children. Not for use during pregnancy or breastfeeding. Consult your doctor before use if you take any medication or are under medical supervision.